Joe is a Canadian surgeon whose career obsession isolates him from his wife and family. When he undergoes surgery himself, he can't resist the little pain pills and becomes addicted. A shadowy transnational group blackmails him into some off-the-record medical work that he can't refuse. COVID takes its toll and recedes, leaving Joe burned out and anxious.

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Just as war breaks out in Europe after decades of peace, Joe receives a diagnosis: a fatal form of dementia. The ring of spies reaches out to him once more with an offer: a free, experimental drug that will augment his memory to miraculous capabilities, in exchange for his medical services as an assassin.

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The drug must be kept at body temperature. Joe devises a technique for performing surgery on himself, becoming his own drug mule, surgeon and IV nurse.  He travels through Europe in the care of the enigmatic Father Boris: an ordained priest, master spy and experienced killer in his own right.

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Joe's team of handlers and volunteers guide him across borders, through traps, betrayals and army camps. His final house call is to the Novo-Ogaryovo palace outside Moscow.